Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.47 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.47 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310404 | 0.89 | POLB (0.62) | POLBHTR2CTSHRL3MBTL1KDM4E | |
| SCHEMBL16356837 | 0.89 | POLB (0.52) | POLBHTR2CTSHRL3MBTL1KDM4E | |
| SCHEMBL8482480 | 0.89 | POLB (0.62) | POLBHTR2CTSHRL3MBTL1KDM4E | |
| SCHEMBL8477698 | 0.89 | POLB (0.62) | POLBHTR2CTSHRL3MBTL1KDM4E | |
| SCHEMBL8477557 | 0.89 | POLB (0.62) | POLBHTR2CTSHRL3MBTL1KDM4E | |
| SCHEMBL8477697 | 0.89 | POLB (0.62) | POLBHTR2CTSHRL3MBTL1KDM4E | |
| SCHEMBL8477564 | 0.89 | POLB (0.62) | POLBHTR2CTSHRL3MBTL1KDM4E | |
| SCHEMBL19120482 | 0.89 | PDK1 (0.52) | TSHRL3MBTL1KDM4ELMNACACNA1A | |
| SCHEMBL16648037 | 0.88 | POLB (0.47) | POLBHTR2CTSHRL3MBTL1KDM4E | |
| SCHEMBL16857493 | 0.87 | POLB (0.53) | POLBHTR2CTSHRL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999054321-A1 | SUBSTITUTED DIAMINES AND THEIR USE AS CELL ADHESION INHIBITORS | AVENTIS PHARMA LIMITED (GB) | 1999-10-28 | — | — | WO | disclosed |