Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | NAT1 | P18440 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7423878 | 1.00 | F2 (0.56) | F2MCL1BCL2A1MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL5866146 | 0.99 | F2 (0.55) | F2MCL1BCL2A1MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL5866145 | 0.99 | F2 (0.55) | F2MCL1BCL2A1MAPTMEN1 | |
| SCHEMBL7606359 | 0.89 | F2 (0.48) | F2MCL1BCL2A1MAPTMEN1 | |
| SCHEMBL7421803 | 0.89 | F2 (0.48) | F2MCL1BCL2A1MAPTMEN1 | |
| SCHEMBL5866388 | 0.89 | F2 (0.62) | F2MCL1BCL2A1MAPTMEN1 | |
| SCHEMBL5866380 | 0.89 | F2 (0.62) | F2MCL1BCL2A1MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL5866335 | 0.88 | F2 (0.48) | F2MCL1BCL2A1MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL5866338 | 0.88 | F2 (0.48) | F2MCL1BCL2A1MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL5866266 | 0.88 | F2 (0.61) | F2MCL1BCL2A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0917528-B1 | NEW AMIDINO DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS | ASTRAZENECA AB (SE) | 2002-09-18 | — | — | EP | disclosed |
| EP-0917528-A1 | NEW AMIDINO DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS | Astra Aktiebolag (SE) | 1999-05-26 | — | — | EP | disclosed |
| WO-1998001422-A1 | NEW AMIDINO DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS | ASTRA AKTIEBOLAG (SE) | 1998-01-15 | — | — | WO | disclosed |