Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.45 |
| ▸ | FABP1 | P07148 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421803 | 1.00 | F2 (0.48) | F2ALDH1A1LMNAPKMHPGD | |
| Hydrochloric Acid SCHEMBL5866335 | 0.99 | F2 (0.48) | F2ALDH1A1LMNAPKMHPGD | |
| Hydrochloric Acid SCHEMBL5866338 | 0.99 | F2 (0.48) | F2ALDH1A1LMNAPKMHPGD | |
| SCHEMBL7423880 | 0.89 | F2 (0.56) | F2ALDH1A1LMNAMCL1BCL2A1 | |
| SCHEMBL7423878 | 0.89 | F2 (0.56) | F2ALDH1A1LMNAMCL1BCL2A1 | |
| Hydrochloric Acid SCHEMBL5866146 | 0.88 | F2 (0.55) | F2ALDH1A1LMNAMCL1BCL2A1 | |
| Hydrochloric Acid SCHEMBL5866145 | 0.88 | F2 (0.55) | F2ALDH1A1LMNAMCL1BCL2A1 | |
| SCHEMBL7428089 | 0.87 | PGR (0.40) | F2ALDH1A1LMNAPKMHPGD | |
| SCHEMBL7428082 | 0.87 | PGR (0.40) | F2ALDH1A1LMNAPKMHPGD | |
| SCHEMBL5866241 | 0.87 | F2 (0.53) | F2CACNA1BFABP1MCL1BCL2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0917528-B1 | NEW AMIDINO DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS | ASTRAZENECA AB (SE) | 2002-09-18 | — | — | EP | disclosed |