Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HTR7 | P34969 | 2/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7423916 | 1.00 | ALDH1A1 (0.63) | ALDH1A1KDM4ESMN1; SMN2HTR7HTR1A | |
| SCHEMBL7420270 | 0.89 | — | — | |
| SCHEMBL7420273 | 0.89 | — | — | |
| SCHEMBL7421937 | 0.89 | ALDH1A1 (0.57) | ALDH1A1KDM4ESMN1; SMN2HTR7HTR1A | |
| SCHEMBL7422589 | 0.89 | ALDH1A1 (0.57) | ALDH1A1KDM4ESMN1; SMN2HTR7HTR1A | |
| SCHEMBL7421926 | 0.89 | ALDH1A1 (0.57) | ALDH1A1KDM4ESMN1; SMN2HTR7HTR1A | |
| SCHEMBL7422590 | 0.89 | ALDH1A1 (0.57) | ALDH1A1KDM4ESMN1; SMN2HTR7HTR1A | |
| SCHEMBL7422585 | 0.89 | ALDH1A1 (0.57) | ALDH1A1KDM4ESMN1; SMN2HTR7HTR1A | |
| SCHEMBL7421931 | 0.89 | ALDH1A1 (0.57) | ALDH1A1KDM4ESMN1; SMN2HTR7HTR1A | |
| Hydrochloric Acid SCHEMBL7416612 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5608069-A | TREATMENT OF NERVOUS SYSTEM DISORDERS WITH GAMMA-AMINOBUTYRIC ACID | NOVO NORDISK A/S (DK) | 1997-03-04 | — | — | US | disclosed |
| EP-0705246-A1 | N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACIDS AND ESTERS THEREOF | NOVO NORDISK A/S (DK) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000483-A1 | N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACIDS AND ESTERS THEREOF | NOVO NORDISK A/S (DK) | 1995-01-05 | — | — | WO | disclosed |