SCHEMBL7423932

SCHEMBL7423932

CCC(C(=O)O)N1CCCN(C(=O)Cc2ccc(NC(=O)Nc3ccccc3C)cc2)CC1

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ITGB1 P05556 20/20 0.52
ITGA4 P13612 20/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7428353 0.96 ITGB1 (0.53) ITGB1ITGA4
SCHEMBL7425123 0.81 ITGB1 (0.72) ITGB1ITGA4
SCHEMBL7431859 0.80 ITGB1 (0.60) ITGB1ITGA4
SCHEMBL7419553 0.79 ITGB1 (0.74) ITGB1ITGA4
SCHEMBL7423940 0.78 ITGB1 (0.58) ITGB1ITGA4
SCHEMBL7421551 0.77 ITGB1 (0.51) ITGB1ITGA4
SCHEMBL7394433 0.77 ITGB1 (0.61) ITGB1ITGA4
SCHEMBL7428355 0.76 ITGB1 (0.59) ITGB1ITGA4
SCHEMBL7424439 0.73 ITGA4 (0.63) ITGB1ITGA4
SCHEMBL29612679 0.72 ITGB1 (0.67) ITGB1ITGA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999054321-A1 SUBSTITUTED DIAMINES AND THEIR USE AS CELL ADHESION INHIBITORS AVENTIS PHARMA LIMITED (GB) 1999-10-28 WO disclosed