Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.91 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.91 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.91 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | HTT | P42858 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | CASP1 | P29466 | 1/20 | 0.61 |
| ▸ | CASP7 | P55210 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1893374 | 0.75 | KMT2A (0.80) | ALDH1A1KDM4EALOX15KMT2AMEN1 | |
| SCHEMBL20943505 | 0.69 | PPARG (0.56) | ALDH1A1KDM4EALOX15KMT2AMEN1 | |
| SCHEMBL15835224 | 0.69 | MAPT (0.58) | ALDH1A1KDM4EALOX15KMT2AMEN1 | |
| SCHEMBL30774052 | 0.68 | RXFP1 (0.82) | ALDH1A1KDM4EALOX15KMT2AMEN1 | |
| SCHEMBL1897337 | 0.68 | MEN1 (0.69) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL12668752 | 0.67 | PPARG (0.57) | ALDH1A1KDM4EALOX15KMT2AMEN1 | |
| SCHEMBL30774054 | 0.66 | MEN1 (0.68) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL1898032 | 0.66 | MEN1 (0.68) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL1896713 | 0.66 | RXFP1 (0.70) | ALDH1A1KDM4EALOX15KMT2AMEN1 | |
| SCHEMBL30774082 | 0.66 | RXFP1 (0.70) | ALDH1A1KDM4EALOX15KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138356-B2 | Chemical inhibitors of inhibitors of differentiation | Angiogeney, Inc. (US) | 2012-03-20 | — | — | US | disclosed |
| US-20090226422-A1 | Chemical Inhibitors of Inhibitors of Differentiation | ANGIOGENEX | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090226422-A1 | Chemical Inhibitors of Inhibitors of Differentiation | BRAF, MAPK1, RAF1 | ALDH1A1 1860/4885KDM4E 1876/4885ALOX15 852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.