Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 7/20 | 0.35 |
| ▸ | FNTB | P49356 | 7/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 7/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7422884 | 0.82 | FNTA (0.50) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL8425435 | 0.81 | F10 (0.60) | F10KLK6F2 | |
| SCHEMBL27478655 | 0.81 | JAK2 (0.35) | F10KLK6JAK2JAK1TYK2 | |
| SCHEMBL7420970 | 0.81 | JAK2 (0.35) | F10KLK6JAK2JAK1TYK2 | |
| SCHEMBL7429676 | 0.81 | JAK2 (0.35) | F10KLK6JAK2JAK1TYK2 | |
| SCHEMBL2331612 | 0.81 | F10 (0.42) | F10KLK6JAK2JAK1TYK2 | |
| SCHEMBL7422879 | 0.80 | SRC (0.46) | — | |
| Hydrochloric Acid SCHEMBL2325599 | 0.80 | JAK2 (0.34) | F10KLK6JAK2JAK1TYK2 | |
| SCHEMBL7420434 | 0.79 | JAK2 (0.34) | F10KLK6JAK2JAK1TYK2 | |
| SCHEMBL7423307 | 0.77 | F10 (0.39) | F10FNTAFNTBPGGT1BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996040679-A1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N-[(AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-12-19 | — | — | WO | disclosed |