SCHEMBL7424592

SCHEMBL7424592

COC(=O)C(N)C(=O)OCc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.55
LTA4H P09960 3/20 0.51
KMT2A Q03164 3/20 0.49
MAPK1 P28482 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
SLC6A2 P23975 1/20 0.49
SLC6A3 Q01959 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
CA12 O43570 2/20 0.47
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
CA9 Q16790 2/20 0.47
TRPM8 Q7Z2W7 1/20 0.47
ALOX15 P16050 1/20 0.47
LAP3 P28838 1/20 0.47
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
SLC1A3 P43003 2/20 0.46
SLC1A2 P43004 2/20 0.46
SLC1A1 P43005 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7694383 0.91 ALDH1A1 (0.59) ALDH1A1LTA4HKMT2AMAPK1L3MBTL1
SCHEMBL3231535 0.86 ALDH1A1 (0.55) ALDH1A1LTA4HKMT2AMAPK1L3MBTL1
Hydrochloric Acid SCHEMBL27925213 0.85 ALDH1A1 (0.53) ALDH1A1LTA4HKMT2AMAPK1L3MBTL1
SCHEMBL9081027 0.84 ALDH1A1 (0.61) ALDH1A1LTA4HKMT2AMAPK1L3MBTL1
SCHEMBL9082362 0.84 ALDH1A1 (0.61) ALDH1A1LTA4HKMT2AMAPK1L3MBTL1
SCHEMBL4788226 0.84 ALDH1A1 (0.55) ALDH1A1LTA4HKMT2AMAPK1L3MBTL1
SCHEMBL20215690 0.83 ALDH1A1 (0.51) ALDH1A1LTA4HKMT2AMAPK1L3MBTL1
SCHEMBL20059193 0.83 ALDH1A1 (0.51) ALDH1A1LTA4HKMT2AMAPK1L3MBTL1
Chloromethane SCHEMBL28952099 0.83 ALDH1A1 (0.51) ALDH1A1LTA4HKMT2AMAPK1L3MBTL1
Hydrochloric Acid SCHEMBL9081024 0.83 ALDH1A1 (0.59) ALDH1A1LTA4HKMT2AMAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104602680-B Molecular aggregate and drug delivery system using branched amphiphilic block polymer 株式会社岛津制作所 2018-02-23 CN disclosed
US-5260278-A Diol-containing renin inhibitors WARNER-LAMBERT COMPANY (US) 1993-11-09 US disclosed
US-5036053-A Peptide WARNER-LAMBERT COMPANY (US) 1991-07-30 US disclosed
EP-0343654-A2 Diol-containing renin inhibitors WARNER-LAMBERT COMPANY (US) 1989-11-29 EP disclosed