Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | PARP1 | P09874 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 2/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1577814 | 0.83 | LMNA (0.67) | LMNAKDM4EPARP1CYP2C19KMT2A | |
| SCHEMBL2873413 | 0.81 | KDM4E (0.62) | KDM4EPARP1CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL27294564 | 0.81 | NQO2 (0.49) | LMNAKDM4EPARP1CYP1A2CYP2C19 | |
| SCHEMBL4299350 | 0.81 | KDM4E (0.62) | KDM4EPARP1CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL30587187 | 0.81 | KDM4E (0.62) | KDM4EPARP1CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL31685132 | 0.81 | NQO2 (0.49) | LMNAKDM4EPARP1CYP1A2CYP2C19 | |
| SCHEMBL29966202 | 0.80 | KDM4E (0.61) | KDM4EPARP1CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL4302340 | 0.80 | KDM4E (0.61) | KDM4EPARP1CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL4298175 | 0.80 | KDM4E (0.61) | KDM4EPARP1CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL27551420 | 0.80 | KDM4E (0.61) | KDM4EPARP1CYP1A2CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071669-A1 | BICYCLIC COMPOUNDS HAVING AN ANTI-THROMBITIC EFFECT | Boehringer Ingelheim Pharma KG (DE) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999054313-A1 | BICYCLIC COMPOUNDS HAVING AN ANTI-THROMBITIC EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-10-28 | — | — | WO | disclosed |