Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.65 |
| ▸ | CHKA | P35790 | 1/20 | 0.62 |
| ▸ | PTGIR | P43119 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | HRH2 | P25021 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17491168 | 0.95 | SIGMAR1 (0.71) | SIGMAR1CHKAPTGIRSMN1; SMN2POLB | |
| SCHEMBL1043090 | 0.87 | SIGMAR1 (0.77) | SIGMAR1CHKAPTGIRSMN1; SMN2HRH3 | |
| SCHEMBL1045386 | 0.87 | SIGMAR1 (0.77) | SIGMAR1CHKAPTGIRSMN1; SMN2HRH3 | |
| SCHEMBL1045927 | 0.86 | PTGIR (0.75) | SIGMAR1CHKAPTGIRSMN1; SMN2HRH3 | |
| Hydrochloric Acid SCHEMBL23850638 | 0.84 | PTGIR (0.73) | SIGMAR1CHKAPTGIRSMN1; SMN2HRH3 | |
| SCHEMBL7430743 | 0.83 | SIGMAR1 (0.70) | SIGMAR1HRH3LMNA | |
| SCHEMBL3171551 | 0.82 | PTGIR (0.81) | SIGMAR1CHKAPTGIRSMN1; SMN2HRH3 | |
| SCHEMBL1043952 | 0.82 | SIGMAR1 (0.85) | SIGMAR1CHKAPTGIRSMN1; SMN2POLB | |
| SCHEMBL20804352 | 0.82 | SIGMAR1 (0.85) | SIGMAR1CHKAPTGIRSMN1; SMN2POLB | |
| SCHEMBL19285228 | 0.82 | SIGMAR1 (0.85) | SIGMAR1CHKAPTGIRSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997044334-A2 | NOVEL PIPERAZINE OR HOMOPIPERAZINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND A PROCESS FOR THEIR PREPARATION | EGIS Gyógyszergyár Rt. (HU) | 1997-11-27 | — | — | WO | disclosed |