SCHEMBL7424670

SCHEMBL7424670

CON(c1ccccc1)[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.46
PPARG P37231 2/20 0.44
PPARA Q07869 2/20 0.44
SRR Q9GZT4 2/20 0.44
ALPI P09923 1/20 0.43
PKM P14618 1/20 0.43
PTGS1 P23219 1/20 0.43
XIAP P98170 1/20 0.43
SLC7A5 Q01650 1/20 0.43
LAP3 P28838 1/20 0.43
MAPT P10636 2/20 0.42
ALDH1A1 P00352 1/20 0.42
ADAMTS5 Q9UNA0 1/20 0.42
SLC1A3 P43003 2/20 0.41
SLC1A2 P43004 2/20 0.41
SLC1A1 P43005 2/20 0.41
CPA1 P15085 2/20 0.41
CPA3 P15088 2/20 0.41
FOLH1 Q04609 1/20 0.41
CPB1 P15086 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7424666 1.00 CYP1A2 (0.46) CYP1A2PPARGPPARASRRALPI
SCHEMBL5281056 0.83 ALDH1A1 (0.38) ALDH1A1KDM4EMEN1POLBCYP2C9
SCHEMBL5281059 0.83 ALDH1A1 (0.38) ALDH1A1KDM4EMEN1POLBCYP2C9
SCHEMBL7743182 0.82 CYP1A2 (0.41) CYP1A2PPARGPPARASRRALPI
SCHEMBL7743185 0.82 CYP1A2 (0.41) CYP1A2PPARGPPARASRRALPI
SCHEMBL3248704 0.81 CYP1A2 (0.50) CYP1A2PPARGPPARASRRALPI
SCHEMBL472008 0.81 CYP1A2 (0.50) CYP1A2PPARGPPARASRRALPI
SCHEMBL3963076 0.81 KMT2A (0.45) CYP1A2ALDH1A1MEN1POLBCYP2C9
SCHEMBL7421113 0.80 CPA1 (0.43) CYP1A2PPARGPPARASRRALPI
SCHEMBL7421118 0.80 CPA1 (0.43) CYP1A2PPARGPPARASRRALPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001012183-A1 HETEROCYCLE AMIDES AS CELL ADHESION INHIBITORS MERCK & CO., INC. (US) 2001-02-22 WO disclosed