Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 7/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1307331 | 0.83 | IDO1 (0.43) | IDO1HTTHIF1ACYP3A4MEN1 | |
| SCHEMBL701343 | 0.83 | CYP2A6 (0.48) | IDO1HTTHIF1ACYP3A4MEN1 | |
| SCHEMBL4574317 | 0.79 | IDO1 (0.43) | IDO1HTTHIF1ACYP3A4MEN1 | |
| SCHEMBL10537631 | 0.79 | IDO1 (0.43) | IDO1HTTHIF1ACYP3A4MEN1 | |
| SCHEMBL29684504 | 0.78 | SMN1; SMN2 (0.48) | IDO1HTTHIF1ACYP3A4MEN1 | |
| SCHEMBL7865951 | 0.78 | SMN1; SMN2 (0.48) | IDO1HTTHIF1ACYP3A4MEN1 | |
| SCHEMBL10898970 | 0.78 | PRKCI (0.36) | HTTMEN1MAPTCASP1BLM | |
| SCHEMBL5107799 | 0.78 | CYP3A4 (0.48) | IDO1HTTHIF1ACYP3A4MEN1 | |
| SCHEMBL9130851 | 0.77 | CYP3A4 (0.43) | IDO1HTTCYP3A4MEN1MAPT | |
| SCHEMBL1560923 | 0.77 | CYP3A4 (0.45) | IDO1HTTHIF1ACYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002022584-A1 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2002-03-21 | — | — | WO | disclosed |