Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20128943 | 0.93 | GPR119 (0.58) | GPR119FAAHHPGDKDM4EPKM | |
| SCHEMBL26655179 | 0.92 | GPR119 (0.49) | GPR119FAAHHPGDKDM4EPKM | |
| SCHEMBL1576008 | 0.88 | GPR119 (0.56) | GPR119FAAHHPGDKDM4EPKM | |
| SCHEMBL7925515 | 0.87 | GPR119 (0.54) | GPR119FAAHHPGDKDM4EPKM | |
| SCHEMBL23499817 | 0.87 | GPR119 (0.57) | GPR119FAAHHPGDKDM4EPKM | |
| SCHEMBL8430037 | 0.87 | GPR119 (0.57) | GPR119FAAHHPGDKDM4EPKM | |
| SCHEMBL560636 | 0.87 | GPR119 (0.55) | GPR119FAAHHPGDKDM4EPKM | |
| SCHEMBL7423589 | 0.85 | GPR119 (0.49) | GPR119FAAHHPGDKDM4EPKM | |
| SCHEMBL20133352 | 0.85 | HPGD (0.45) | GPR119HPGDRECQLEPHX1 | |
| SCHEMBL4227407 | 0.84 | GPR119 (0.48) | GPR119FAAHHPGDKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815103-A1 | TRYPSIN AND THROMBIN INHIBITORS | Novartis AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996029327-A1 | TRYPSIN AND THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1996-09-26 | — | — | WO | disclosed |