Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.51 |
| ▸ | ACE | P12821 | 3/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 11/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 11/20 | 0.38 |
| ▸ | FNTA | P49354 | 3/20 | 0.32 |
| ▸ | FNTB | P49356 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425379 | 0.89 | ACE2 (0.55) | ACE2ACECYP11B1CYP11B2FNTA | |
| SCHEMBL7421725 | 0.87 | ACE2 (0.51) | ACE2ACECYP11B1CYP11B2FNTA | |
| SCHEMBL1655470 | 0.86 | ACE2 (0.59) | ACE2ACECYP11B1CYP11B2FNTA | |
| SCHEMBL1655482 | 0.86 | ACE2 (0.59) | ACE2ACECYP11B1CYP11B2FNTA | |
| SCHEMBL7531327 | 0.82 | ACE2 (0.52) | ACE2ACECYP11B1CYP11B2FNTA | |
| SCHEMBL7384406 | 0.81 | ACE2 (0.54) | ACE2ACECYP11B1CYP11B2FNTA | |
| SCHEMBL3712452 | 0.79 | ACE2 (0.41) | ACE2ACECYP11B1CYP11B2FNTA | |
| SCHEMBL7424859 | 0.79 | ACE2 (0.51) | ACE2ACECYP11B1CYP11B2FNTA | |
| SCHEMBL1656651 | 0.78 | CYP11B1 (0.52) | ACE2ACECYP11B1CYP11B2FNTA | |
| SCHEMBL3681437 | 0.77 | ACE2 (0.48) | ACE2ACECYP11B1CYP11B2FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | disclosed |