Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7423627 | 0.84 | FKBP1A (0.39) | NPC1RAB9AL3MBTL1MAPK1CCR5 | |
| SCHEMBL8810505 | 0.77 | ELANE (0.45) | NPC1RAB9ASMN1; SMN2L3MBTL1GAA | |
| SCHEMBL1188239 | 0.76 | PREP (0.42) | CCR5CYP2C19 | |
| SCHEMBL6135688 | 0.76 | PREP (0.42) | CCR5CYP2C19 | |
| SCHEMBL23177206 | 0.74 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2L3MBTL1GAA | |
| SCHEMBL8236318 | 0.74 | SMN1; SMN2 (0.68) | NPC1RAB9ASMN1; SMN2CYP2C19 | |
| SCHEMBL4391983 | 0.73 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2L3MBTL1GAA | |
| SCHEMBL7424833 | 0.72 | TSHR (0.45) | L3MBTL1GAAMAPK1CCR5CYP2C19 | |
| SCHEMBL1766231 | 0.72 | HTR2C (0.60) | NPC1RAB9ASMN1; SMN2L3MBTL1CYP2C19 | |
| SCHEMBL29707055 | 0.72 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925289-A1 | MATRIX METALLOPROTEINASE INHIBITORS | PHARMACIA & UPJOHN S.p.A. (IT) | 1999-06-30 | — | — | EP | disclosed |
| WO-1999002510-A1 | MATRIX METALLOPROTEINASE INHIBITORS | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-01-21 | — | — | WO | disclosed |