Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.53 |
| ▸ | F2 | P00734 | 8/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 5/20 | 0.42 |
| ▸ | YWHAH | Q04917 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | FURIN | P09958 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430422 | 0.94 | F10 (0.51) | F10F2PRSS1PLA2G2A | |
| SCHEMBL7433924 | 0.94 | F10 (0.54) | F10F2PRSS1PLA2G2A | |
| SCHEMBL7427399 | 0.93 | F10 (0.65) | F10F2PRSS1 | |
| SCHEMBL7433846 | 0.91 | F10 (0.51) | F10F2PRSS1PLA2G2AYWHAH | |
| SCHEMBL7430190 | 0.90 | F10 (0.55) | F10F2PRSS1FURIN | |
| SCHEMBL7428513 | 0.88 | F10 (0.52) | F10F2PRSS1PLA2G2A | |
| SCHEMBL7424253 | 0.85 | F10 (0.52) | F10F2PRSS1 | |
| SCHEMBL7427220 | 0.84 | F10 (0.54) | F10F2PRSS1 | |
| SCHEMBL7420509 | 0.83 | F10 (0.68) | F10F2PRSS1 | |
| SCHEMBL7420549 | 0.74 | F2 (0.60) | F10F2PRSS1FURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107954-A1 | 2-OXO-$i(2H)-QUINOLINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012479-A1 | 2-OXO-2H-QUINOLINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-03-09 | — | — | WO | disclosed |