Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.65 |
| ▸ | F2 | P00734 | 16/20 | 0.65 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.65 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7424892 | 0.93 | F10 (0.53) | F10F2PRSS1 | |
| SCHEMBL7430422 | 0.92 | F10 (0.51) | F10F2PRSS1 | |
| SCHEMBL7420509 | 0.91 | F10 (0.68) | F10F2PRSS1 | |
| SCHEMBL7433924 | 0.87 | F10 (0.54) | F10F2PRSS1 | |
| SCHEMBL7428513 | 0.86 | F10 (0.52) | F10F2PRSS1 | |
| SCHEMBL7433846 | 0.84 | F10 (0.51) | F10F2PRSS1 | |
| SCHEMBL7424253 | 0.83 | F10 (0.52) | F10F2PRSS1 | |
| SCHEMBL7430190 | 0.83 | F10 (0.55) | F10F2PRSS1 | |
| SCHEMBL7425811 | 0.82 | F2 (0.72) | F10F2PRSS1 | |
| SCHEMBL7427220 | 0.82 | F10 (0.54) | F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107954-A1 | 2-OXO-$i(2H)-QUINOLINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012479-A1 | 2-OXO-2H-QUINOLINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-03-09 | — | — | WO | disclosed |