Sugi Predict

Sugi Predict / Compounds / SCHEMBL7424895

SCHEMBL7424895

SCHEMBL7424895

Cc1cc(=O)n(Cc2cccc(C(=N)N)c2)c2c(Oc3cccc(C(=N)N)c3)cccc12

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ ATM Q13315 1/20 0.48
▸ F10 P00742 17/20 0.48
▸ F2 P00734 6/20 0.46
▸ PRSS1 P07477 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7424887 0.83 F10 (0.56) F10F2PRSS1
SCHEMBL7433462 0.76 F10 (0.48) F10F2PRSS1
SCHEMBL7425811 0.74 F2 (0.72) F10F2PRSS1
SCHEMBL7430906 0.74 F10 (0.67) F10F2PRSS1
SCHEMBL8443630 0.72 F10 (0.57) F10F2PRSS1
SCHEMBL8442920 0.70 F10 (0.57) F10F2PRSS1
SCHEMBL7427220 0.70 F10 (0.54) F10F2PRSS1
SCHEMBL7427280 0.69 F2 (0.55) F10F2
SCHEMBL7428513 0.69 F10 (0.52) F10F2PRSS1
SCHEMBL8443660 0.69 F10 (0.61) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1107954-A1 2-OXO-$i(2H)-QUINOLINE DERIVATIVES MERCK PATENT GmbH (DE) 2001-06-20 — — EP claimed
WO-2000012479-A1 2-OXO-2H-QUINOLINE DERIVATIVES MERCK PATENT GMBH (DE) 2000-03-09 — — WO claimed
EP-1107954-A1 2-OXO-$i(2H)-QUINOLINE DERIVATIVES MERCK PATENT GmbH (DE) 2001-06-20 — — EP disclosed
WO-2000012479-A1 2-OXO-2H-QUINOLINE DERIVATIVES MERCK PATENT GMBH (DE) 2000-03-09 — — WO disclosed