Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.48 |
| ▸ | F2 | P00734 | 12/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.48 |
| ▸ | FURIN | P09958 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430819 | 0.84 | F2 (0.52) | F10F2 | |
| SCHEMBL7420549 | 0.83 | F2 (0.60) | F10F2PRSS1FURIN | |
| SCHEMBL7433456 | 0.82 | F10 (0.56) | F10F2PRSS1FURIN | |
| SCHEMBL7432569 | 0.79 | F10 (0.49) | F10F2 | |
| SCHEMBL7427280 | 0.79 | F2 (0.55) | F10F2 | |
| SCHEMBL7425231 | 0.78 | F10 (0.47) | F10F2 | |
| SCHEMBL7424895 | 0.76 | ATM (0.48) | F10F2PRSS1 | |
| SCHEMBL7423757 | 0.72 | F2 (0.61) | F10F2PRSS1 | |
| SCHEMBL7430809 | 0.71 | F2 (0.63) | F10F2 | |
| SCHEMBL7430906 | 0.68 | F10 (0.67) | F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107954-A1 | 2-OXO-$i(2H)-QUINOLINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012479-A1 | 2-OXO-2H-QUINOLINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-03-09 | — | — | WO | disclosed |