Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7424929 | 1.00 | NPSR1 (0.50) | NPSR1ALOX15HCAR2ALDH1A1LMNA | |
| SCHEMBL7913300 | 1.00 | NPSR1 (0.50) | NPSR1ALOX15HCAR2ALDH1A1LMNA | |
| SCHEMBL7912959 | 0.83 | NPSR1 (0.54) | NPSR1ALOX15HCAR2ALDH1A1LMNA | |
| SCHEMBL3190948 | 0.83 | NPSR1 (0.54) | NPSR1ALOX15HCAR2ALDH1A1LMNA | |
| SCHEMBL4753860 | 0.83 | NPSR1 (0.54) | NPSR1ALOX15HCAR2ALDH1A1LMNA | |
| SCHEMBL8201155 | 0.79 | NPSR1 (0.50) | NPSR1ALOX15HCAR2ALDH1A1LMNA | |
| SCHEMBL1061977 | 0.79 | NPSR1 (0.50) | NPSR1ALOX15HCAR2ALDH1A1LMNA | |
| SCHEMBL7598957 | 0.79 | NPSR1 (0.46) | NPSR1ALOX15HCAR2ALDH1A1LMNA | |
| SCHEMBL24116900 | 0.78 | — | — | |
| SCHEMBL7428622 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4686217-A | HYPOTENSIVE AGENTS, CARDIOVASCULAR DISORDERS | FISONS PLC (GB) | 1987-08-11 | — | — | US | disclosed |
| US-4607041-A | CARDIOTONIC AGENTS | FISONS PLC (GB) | 1986-08-19 | — | — | US | disclosed |
| EP-0125803-A2 | Pharmaceutically active dihydropyridines | FISONS plc (GB) | 1984-11-21 | — | — | EP | disclosed |