Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3190948 | 1.00 | NPSR1 (0.54) | NPSR1ALOX15HCAR2SOAT1ALDH1A1 | |
| SCHEMBL7912959 | 1.00 | NPSR1 (0.54) | NPSR1ALOX15HCAR2SOAT1ALDH1A1 | |
| SCHEMBL1061977 | 0.83 | NPSR1 (0.50) | NPSR1ALOX15HCAR2SOAT1ALDH1A1 | |
| SCHEMBL7424929 | 0.83 | NPSR1 (0.50) | NPSR1ALOX15HCAR2SOAT1ALDH1A1 | |
| SCHEMBL8201155 | 0.83 | NPSR1 (0.50) | NPSR1ALOX15HCAR2SOAT1ALDH1A1 | |
| SCHEMBL7424926 | 0.83 | NPSR1 (0.50) | NPSR1ALOX15HCAR2SOAT1ALDH1A1 | |
| SCHEMBL7913300 | 0.83 | NPSR1 (0.50) | NPSR1ALOX15HCAR2SOAT1ALDH1A1 | |
| SCHEMBL1680637 | 0.81 | — | — | |
| SCHEMBL4807139 | 0.81 | NPSR1 (0.48) | NPSR1ALOX15HCAR2SOAT1ALDH1A1 | |
| SCHEMBL4807131 | 0.81 | NPSR1 (0.48) | NPSR1ALOX15HCAR2SOAT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326389-B1 | Process for preparing 4-hydroxypyrimidine | UBE INDUSTRIES (JP) | 1996-09-11 | — | — | EP | claimed |
| US-4935516-A | Process for preparing 4-hydroxypyrimidine | UBE INDUSTRIES, LTD. (JP) | 1990-06-19 | — | — | US | claimed |
| US-20230303545-A1 | PREPARATION METHOD OF PHENYLISOXAZOLINE COMPOUND | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2023-09-28 | — | — | US | disclosed |
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |
| EP-0326389-B1 | Process for preparing 4-hydroxypyrimidine | UBE INDUSTRIES (JP) | 1996-09-11 | — | — | EP | disclosed |
| US-5502057-A | Polysubstituted pyridines useful for treating lipoproteinanaemia and arteriosclerosis | BAYER AKTIENGESELLSCHAFT (DE) | 1996-03-26 | — | — | US | disclosed |
| US-5470982-A | Disubstituted pyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1995-11-28 | — | — | US | disclosed |
| US-5173495-A | 7-[(2,6-dialkyl-4-furyl or thienyl-pyridyl)]-3,5-di-(dihydroxy-6-enoates) useful for treating circulatory diseases | BAYER AKTIENGESELLSCHAFT (DE) | 1992-12-22 | — | — | US | disclosed |
| US-5142055-A | Dehydrofluorinating reduced fluoroalkyl pyridine compound | MONSANTO COMPANY (US) | 1992-08-25 | — | — | US | disclosed |
| US-5098462-A | Herbicides | SANDOZ LTD. (CH) | 1992-03-24 | — | — | US | disclosed |
| US-5098466-A | Herbicides | SANDOZ LTD. (CH) | 1992-03-24 | — | — | US | disclosed |
| US-4692184-A | HERBICIDES | MONSANTO COMPANY (US) | 1987-09-08 | — | — | US | disclosed |
| EP-0135491-A1 | Herbicidal 2,6-bis-fluoromethyl-dihydropyridine-3,5-dicarboxylic acid esters | MONSANTO COMPANY (US) | 1985-03-27 | — | — | EP | disclosed |
| EP-0133612-A2 | Substituted 2,6-substituted pyridine compounds | MONSANTO COMPANY (US) | 1985-02-27 | — | — | EP | disclosed |
| US-4358606-A | Esters of phenalkyloxycarbonylamino acids | ZOECON CORPORATION (US) | 1982-11-09 | — | — | US | disclosed |
| US-4147528-A | 6-Oxopyrimidine plant growth regulators | ROHM AND HAAS COMPANY (US) | 1979-04-03 | — | — | US | disclosed |
| US-3946028-A | HYPOTENSIVE AGENTS, CORONARY VESSEL DILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-23 | — | — | US | disclosed |
| US-3946027-A | HYPOTENSIVE AGENTS, CORONARY VESSEL DILATORS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-23 | — | — | US | disclosed |
| US-3943140-A | HYPOTENSIVE, VASODILATION | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-09 | — | — | US | disclosed |
| US-3932645-A | CORONARY VASODILATORS, HYPOTENSIVE AGENTS | FARBENFABRIKEN BAYER AG (DT) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303545-A1 | PREPARATION METHOD OF PHENYLISOXAZOLINE COMPOUND | UMPS, UGT1A7, UGT2B7 | NPSR1 3609/4885ALOX15 3642/4885HCAR2 1876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.