SCHEMBL7425004

SCHEMBL7425004

COc1cc(CC(=O)NC(C)C2CCN(C(CC(=O)O)c3ccccc3)CC2)ccc1NC(=O)Nc1ccccc1C

nearest known ligand 0.60

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ITGA4 P13612 18/20 0.60
ITGB1 P05556 17/20 0.60
P2RX7 Q99572 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7535872 0.95 ITGA4 (0.58) ITGA4ITGB1P2RX7
SCHEMBL7425381 0.94 ITGA4 (0.59) ITGA4ITGB1P2RX7
SCHEMBL7428863 0.92 ITGA4 (0.61) ITGA4ITGB1P2RX7
SCHEMBL7424832 0.90 ITGA4 (0.57) ITGA4ITGB1P2RX7
SCHEMBL7430128 0.87 ITGA4 (0.59) ITGA4ITGB1P2RX7
SCHEMBL7431406 0.86 ITGA4 (0.63) ITGA4ITGB1P2RX7
SCHEMBL7425429 0.85 ITGA4 (0.56) ITGA4ITGB1P2RX7
SCHEMBL7426901 0.84 ITGA4 (0.55) ITGA4ITGB1P2RX7
SCHEMBL7430374 0.83 ITGA4 (0.64) ITGA4ITGB1
SCHEMBL7539582 0.82 ITGA4 (0.55) ITGA4ITGB1P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999054321-A1 SUBSTITUTED DIAMINES AND THEIR USE AS CELL ADHESION INHIBITORS AVENTIS PHARMA LIMITED (GB) 1999-10-28 WO disclosed