Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 18/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | XBP1 | P17861 | 1/20 | 0.57 |
| ▸ | PDE6C | P51160 | 1/20 | 0.50 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7427820 | 0.86 | PDE5A (0.58) | PDE5AKDM4EXBP1PDE6CPDE11A | |
| SCHEMBL7541539 | 0.84 | PDE5A (0.62) | PDE5APDE6CPDE11A | |
| SCHEMBL5827475 | 0.83 | PDE5A (0.75) | PDE5APDE6CPDE11A | |
| SCHEMBL5827664 | 0.82 | PDE5A (0.74) | PDE5APDE6CPDE11A | |
| SCHEMBL973387 | 0.75 | PDE5A (0.75) | PDE5APDE6CPDE11A | |
| SCHEMBL3836975 | 0.75 | PDE5A (0.76) | PDE5APDE6CPDE11A | |
| SCHEMBL5827328 | 0.74 | PDE5A (0.89) | PDE5APDE6CPDE11A | |
| SCHEMBL5827394 | 0.74 | PDE5A (0.59) | PDE5A | |
| SCHEMBL5827707 | 0.74 | PDE5A (0.77) | PDE5APDE6CPDE11A | |
| SCHEMBL5827741 | 0.74 | PDE5A (0.88) | PDE5APDE6CPDE11A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999062905-A1 | 8-PHENYLXANTHINE DERIVATIVES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | ALMIRALL PRODESFARMA, S.A. (ES) | 1999-12-09 | — | — | WO | disclosed |