Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.43 |
| ▸ | FDPS | P14324 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20734981 | 0.86 | ALOX15 (0.45) | ALOX15ALDH1A1GGPS1FDPSUSP2 | |
| SCHEMBL20735157 | 0.85 | ALOX15 (0.44) | ALOX15ALDH1A1GGPS1FDPSHDAC3 | |
| SCHEMBL1617378 | 0.82 | ALOX15 (0.54) | ALOX15ALDH1A1GGPS1FDPSUSP2 | |
| SCHEMBL25317905 | 0.82 | ALOX15 (0.54) | ALOX15ALDH1A1GGPS1FDPSUSP2 | |
| SCHEMBL25689380 | 0.81 | ALOX15 (0.53) | ALOX15ALDH1A1GGPS1FDPSUSP2 | |
| SCHEMBL23707013 | 0.81 | ALOX15 (0.62) | ALOX15ALDH1A1GGPS1FDPSUSP2 | |
| SCHEMBL29645274 | 0.81 | ALOX15 (0.57) | ALOX15ALDH1A1GGPS1FDPSUSP2 | |
| SCHEMBL20734974 | 0.79 | ALOX15 (0.56) | ALOX15ALDH1A1GGPS1FDPSUSP2 | |
| SCHEMBL23706999 | 0.79 | ALOX15 (0.52) | ALOX15ALDH1A1GGPS1FDPSUSP2 | |
| SCHEMBL12446349 | 0.79 | ALOX15 (0.56) | ALOX15ALDH1A1GGPS1FDPSUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174457-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | UNIV IOWA STATE RES FOUND INC (US) | 2023-06-08 | — | — | US | claimed |
| US-20240391864-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | UNIV IOWA STATE RES FOUND INC (US) | 2024-11-28 | — | — | US | disclosed |
| EP-4382518-A2 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | Iowa State University Research Foundation, Inc. (US) | 2024-06-12 | — | — | EP | disclosed |
| EP-3503733-B1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | UNIV IOWA STATE RES FOUND INC (US) | 2024-03-20 | — | — | EP | disclosed |
| US-20230174457-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | UNIV IOWA STATE RES FOUND INC (US) | 2023-06-08 | — | — | US | disclosed |
| US-20230174457-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | UNIV IOWA STATE RES FOUND INC (US) | 2023-06-08 | — | — | US | disclosed |
| US-20230174457-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | UNIV IOWA STATE RES FOUND INC (US) | 2023-06-08 | — | — | US | disclosed |
| US-11485701-B2 | Insect repellent compounds and compositions, and methods thereof | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2022-11-01 | — | — | US | disclosed |
| US-11485701-B2 | Insect repellent compounds and compositions, and methods thereof | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2022-11-01 | — | — | US | disclosed |
| US-20190047937-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2019-02-14 | — | — | US | disclosed |
| US-6372883-B1 | FOR THERAPY AND PROPHYLAXIS OF INFECTIONS CAUSED BY HEPATITIS C, HEPATITIS G AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2002-04-16 | — | — | US | disclosed |
| US-6018020-A | VIRICIDES WHICH ARE PROTEASE INHIBITORS AGAINST HEPATITIS C AND HEPATITIS G | HOFFMAN-LA ROCHE INC. (US) | 2000-01-25 | — | — | US | disclosed |
| EP-0941233-A2 | ANTIVIRAL PEPTIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-09-15 | — | — | EP | disclosed |
| US-5866684-A | Peptidyl inhibitors of viral proteases | HOFFMANN-LA ROCHE INC. (US) | 1999-02-02 | — | — | US | disclosed |
| WO-1998022496-A2 | ANTIVIRAL PEPTIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1998-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11485701-B2 | Insect repellent compounds and compositions, and methods thereof | C5, CYP51A1, DDT | ALOX15 68/4885ALDH1A1 2604/4885GGPS1 244/4885 |
| US-20190047937-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | C5, CYP51A1, DDT | ALOX15 68/4885ALDH1A1 2604/4885GGPS1 244/4885 |
| US-20230174457-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | C5, CYP51A1, DDT | ALOX15 68/4885ALDH1A1 2604/4885GGPS1 244/4885 |
| US-20240391864-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | C5, CYP51A1, DDT | ALOX15 68/4885ALDH1A1 2604/4885GGPS1 244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.