SCHEMBL74253

SCHEMBL74253

O=NC(=O)CS

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16070362 0.73
SCHEMBL14641650 0.69 LMNA (0.31)
SCHEMBL13705935 0.69
SCHEMBL1905514 0.67
SCHEMBL16199849 0.66 FOLH1 (0.50)
SCHEMBL1334923 0.65
SCHEMBL6470561 0.64
SCHEMBL18862808 0.64 SLC22A6 (0.39)
SCHEMBL879224 0.64
SCHEMBL12487494 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1392 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727950-A1 HETEROCYCLIC COMPOUNDS AND THEIR USE IN THE TREATMENT OF MYCOBACTERIAL INFECTIONS GlaxoSmithKline Intellectual Property Development Ltd (GB) 2026-04-22 EP claimed
EP-4121058-B1 OXAZOLIDINONE COMPOUND AND ITS USE THEREOF AS AN ANTIBACTERIAL AGENT MERCK SHARP & DOHME LLC (US) 2026-02-18 EP claimed
US-12459933-B2 Compounds and methods of use thereof as antibacterial agents MERCK SHARP & DOHME LLC (US) 2025-11-04 US claimed
US-12435077-B2 Oxazolidinone compound and methods of use thereof as an antibacterial agent MERCK SHARP & DOHME LLC (US) 2025-10-07 US claimed
US-20250302926-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF ACTINOMYCETIA INFECTIONS ENDOLYTIX TECH INC (US) 2025-10-02 US claimed
US-20250249079-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF ACTINOMYCETIA INFECTIONS ENDOLYTIX TECHNOLOGY, INC. 2025-08-07 US claimed
US-12365656-B2 Oxazolidinone compounds and methods of use thereof as antibacterial agents MERCK SHARP & DOHME LLC (US) 2025-07-22 US claimed
WO-2025096791-A1 A NOVEL COMPOUND ACTING AGAINST A SELECT GROUP OF BACTERIA NORTHEASTERN UNIVERSITY (US) 2025-05-08 WO claimed
US-20250129084-A1 Compounds GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2025-04-24 US claimed
EP-4518840-A2 COMPOSITIONS AND METHODS FOR THE TREATMENT OF ACTINOMYCETIA INFECTIONS Endolytix Technology, Inc. (US) 2025-03-12 EP claimed
EP-1115417-A2 METHODS FOR ADMINISTRATION OF ANTIBIOTICS Cubist Pharmaceuticals, Inc. (US) 2001-07-18 EP claimed
WO-2001044272-A2 DAPTOMYCIN ANALOGS AS ANTIBACTERIAL AGENTS CUBIST PHARMACEUTICALS, INC. (US) 2001-06-21 WO claimed
WO-2001044274-A1 LIPOPEPTIDES AS ANTIBACTERIAL AGENTS CUBIST PHARMACEUTICALS, INC. (US) 2001-06-21 WO claimed
WO-2001044271-A2 DAPTOMYCIN ANALOGS AND THEIR USE AS ANTIBACTERIAL AGENTS CUBIST PHARMACEUTICALS, INC. (US) 2001-06-21 WO claimed
US-6054133-A Anti-microbial targeting for intracellular pathogens THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2000-04-25 US claimed
WO-2000018419-A2 METHODS FOR ADMINISTRATION OF ANTIBIOTICS CUBIST PHARMACEUTICALS, INC. (US) 2000-04-06 WO claimed
CN-1244660-A CO sensor and its producing method FIGARO ENG (JP) 2000-02-16 CN claimed
US-5858410-A Pharmaceutical nanosuspensions for medicament administration as systems with increased saturation solubility and rate of solution MEDAC GESELLSCHAFT FUR KLINISCHE SPEZIALPRAPARATE (DE) 1999-01-12 US claimed
CN-1134278-A Aerosol for preventing and curing pulmonary tuberculosis and its preparing method and synergy method CONG FANZI (CN) 1996-10-30 CN claimed
US-5104875-A Mycobacterial infection; aids FATOL ARZNEIMITTEL GMBH (DE) 1992-04-14 US claimed