Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 6/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425321 | 1.00 | MEN1 (0.40) | MEN1MAPTKMT2ANPSR1MCHR1 | |
| SCHEMBL7425327 | 1.00 | MEN1 (0.40) | MEN1MAPTKMT2ANPSR1MCHR1 | |
| SCHEMBL6983678 | 0.92 | MEN1 (0.41) | MEN1MAPTKMT2ANPSR1F10 | |
| SCHEMBL6985341 | 0.92 | MEN1 (0.41) | MEN1MAPTKMT2ANPSR1F10 | |
| SCHEMBL6983679 | 0.92 | MEN1 (0.41) | MEN1MAPTKMT2ANPSR1F10 | |
| SCHEMBL6978936 | 0.80 | ALDH1A1 (0.48) | MEN1MAPTKMT2ANPSR1ALDH1A1 | |
| SCHEMBL6978940 | 0.80 | ALDH1A1 (0.48) | MEN1MAPTKMT2ANPSR1ALDH1A1 | |
| SCHEMBL6978933 | 0.80 | ALDH1A1 (0.48) | MEN1MAPTKMT2ANPSR1ALDH1A1 | |
| SCHEMBL6978851 | 0.80 | F10 (0.54) | F10PRSS1 | |
| SCHEMBL6978845 | 0.80 | F10 (0.54) | F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934265-A1 | AMIDINOPHENYL-PYRROLIDINES, -PYRROLINES, AND -ISOXAZOLIDINES AND DERIVATIVES THEREOF | Du Pont Pharmaceuticals Company (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998006694-A1 | AMIDINOPHENYL-PYRROLIDINES, -PYRROLINES, AND -ISOXAZOLIDINES AND DERIVATIVES THEREOF | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-02-19 | — | — | WO | disclosed |