Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.35 |
| ▸ | FDPS | P14324 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8059226 | 0.88 | ALOX15 (0.67) | ALOX15ALDH1A1NFE2L2USP2TDP1 | |
| SCHEMBL872688 | 0.83 | ALOX15 (0.61) | ALOX15ALDH1A1NFE2L2USP2TDP1 | |
| SCHEMBL4941959 | 0.83 | ALOX15 (0.61) | ALOX15ALDH1A1NFE2L2USP2TDP1 | |
| SCHEMBL17955374 | 0.82 | ALOX15 (0.65) | ALOX15ALDH1A1NFE2L2USP2TDP1 | |
| SCHEMBL14581768 | 0.82 | ALOX15 (0.65) | ALOX15ALDH1A1NFE2L2USP2TDP1 | |
| SCHEMBL4448966 | 0.82 | ALOX15 (0.65) | ALOX15ALDH1A1NFE2L2USP2TDP1 | |
| SCHEMBL3753013 | 0.81 | ALOX15 (0.54) | ALOX15ALDH1A1NFE2L2USP2TDP1 | |
| SCHEMBL8397532 | 0.80 | ALOX15 (0.67) | ALOX15ALDH1A1NFE2L2USP2TDP1 | |
| SCHEMBL21300623 | 0.79 | ALOX15 (0.60) | ALOX15ALDH1A1NFE2L2USP2TDP1 | |
| SCHEMBL4941988 | 0.79 | ALOX15 (0.56) | ALOX15ALDH1A1NFE2L2USP2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994022820-A1 | 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-10-13 | — | — | WO | disclosed |