Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | RECQL | P46063 | 2/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7419855 | 0.93 | POLB (0.62) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL7427816 | 0.87 | PDE4A (0.59) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL7418279 | 0.87 | NPSR1 (0.62) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL15831619 | 0.86 | KMT2A (0.68) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL7422586 | 0.79 | ALDH1A1 (0.60) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL7415584 | 0.78 | SMN1; SMN2 (0.78) | ALDH1A1KMT2AMAPTPOLBLMNA | |
| SCHEMBL13297941 | 0.77 | KMT2A (0.91) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL12793686 | 0.77 | KMT2A (0.72) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL4182162 | 0.77 | KMT2A (0.77) | ALDH1A1KMT2APOLBLMNAMAPK1 | |
| SCHEMBL11554210 | 0.77 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996036595-A1 | 3,4-DISUBSTITUTED-PHENYLSULPHONAMIDES AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1996-11-21 | — | — | WO | disclosed |