Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7391354 | 0.99 | HPGD (0.64) | HPGDRECQLMAPTNPC1RAB9A | |
| SCHEMBL8162691 | 0.96 | HPGD (0.72) | HPGDRECQLMAPTNPC1RAB9A | |
| SCHEMBL5909732 | 0.84 | ALDH1A1 (0.67) | HPGDRECQLMAPTNPC1RAB9A | |
| SCHEMBL6339534 | 0.84 | SMN1; SMN2 (0.64) | MAPTNPC1RAB9AALDH1A1TSHR | |
| SCHEMBL18117677 | 0.83 | HPGD (0.62) | HPGDRECQLMAPTNPC1RAB9A | |
| SCHEMBL8169533 | 0.82 | ALDH1A1 (0.72) | MAPTNPC1RAB9AALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL11683217 | 0.82 | SMN1; SMN2 (0.62) | MAPTNPC1RAB9AALDH1A1TSHR | |
| SCHEMBL3428262 | 0.82 | HPGD (0.72) | HPGDRECQLMAPTNPC1RAB9A | |
| SCHEMBL4913462 | 0.82 | TSHR (0.69) | HPGDRECQLMAPTNPC1RAB9A | |
| SCHEMBL1994995 | 0.82 | ALDH1A1 (0.80) | HPGDRECQLMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712257-A | COMPLEXED WITH SURFACTANT; VIRICIDES; ANTIFERTILITY AGENTS, CONTRACEPTIVES | HEM RESEARCH, INC. (US) | 1998-01-27 | — | — | US | disclosed |
| EP-0603266-A4 | USE OF HALOALKYL DERIVATIVES OF REPORTER MOLECULES TO ANALYZE METABOLIC ACTIVITY IN CELLS. | MOLECULAR PROBES INC (US) | 1997-01-15 | — | — | EP | disclosed |
| EP-0303516-B1 | Topically active compositions of double-stranded RNAs | HEM PHARMA CORP (US) | 1994-07-06 | — | — | EP | disclosed |
| EP-0603266-A1 | USE OF HALOALKYL DERIVATIVES OF REPORTER MOLECULES TO ANALYZE METABOLIC ACTIVITY IN CELLS | MOLECULAR PROBES, INC. (US) | 1994-06-29 | — | — | EP | disclosed |
| WO-1993004192-A1 | USE OF HALOALKYL DERIVATIVES OF REPORTER MOLECULES TO ANALYZE METABOLIC ACTIVITY IN CELLS | MOLECULAR PROBES, INC. (US) | 1993-03-04 | — | — | WO | disclosed |
| EP-0303516-A2 | Topically active compositions of double-stranded RNAs | HEM PHARMACEUTICALS CORP. (US) | 1989-02-15 | — | — | EP | disclosed |
| US-4423069-A | Contraceptive method | UNIVERSITY OF ILLINOIS FOUNDATION (US) | 1983-12-27 | — | — | US | disclosed |