SCHEMBL7425907

SCHEMBL7425907

CN1C[C@H]2C[C@H](N)C[C@@H](C1)N2C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
CYP2C9 P11712 1/20 0.33
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6953885 1.00 LMNA (0.33) LMNACYP2C9MAPK1
SCHEMBL7431051 1.00 LMNA (0.33) LMNACYP2C9MAPK1
Hydrochloric Acid SCHEMBL1005523 0.97 LMNA (0.32) LMNACYP2C9
Hydrochloric Acid SCHEMBL1005521 0.97 LMNA (0.32) LMNACYP2C9
SCHEMBL23315663 0.83
SCHEMBL2736039 0.83
SCHEMBL18069713 0.83
SCHEMBL12593645 0.80
SCHEMBL6957717 0.78 LMNA (0.30) LMNACYP2C9
SCHEMBL6957714 0.78 LMNA (0.30) LMNACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0469449-B1 Diazabicyclononyl derivatives as 5-HT3 receptor antagonists NISSHIN FLOUR MILLING CO (JP) 1997-10-01 EP disclosed
US-5256656-A Antiserotonine agent NISSHIN FLOUR MILLING CO., LTD. (JP) 1993-10-26 US disclosed
US-5187166-A Also useful as antipsychotic agents NISSHIN FLOUR MILLING CO., LTD. (JP) 1993-02-16 US disclosed
EP-0469449-A1 Azabicyclo derivatives NISSHIN FLOUR MILLING CO., LTD. (JP) 1992-02-05 EP disclosed