Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL777046 | 0.79 | ALDH1A1 (0.50) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL9312379 | 0.73 | ALDH1A1 (0.43) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL180685 | 0.72 | ALDH1A1 (0.56) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL3626577 | 0.71 | ALDH1A1 (0.42) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL27962643 | 0.71 | ALDH1A1 (0.53) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL777939 | 0.70 | ALDH1A1 (0.54) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL1148875 | 0.70 | ALDH1A1 (0.54) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL1412844 | 0.70 | ALDH1A1 (0.54) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL1660614 | 0.69 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2KMT2AMEN1GAA | |
| SCHEMBL1910 | 0.69 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0333661-B1 | Process for the preparation of a pyrole derivative | CIBA GEIGY AG (CH) | 1994-04-27 | — | — | EP | claimed |
| EP-0656025-B2 | SOLUTION FOR COATING NON CONDUCTORS WITH CONDUCTIVE POLYMERS AND THEIR METALLIZATION PROCESS | ATOTECH DEUTSCHLAND GMBH (DE) | 2000-09-27 | — | — | EP | disclosed |
| EP-0656025-B1 | SOLUTION FOR COATING NON CONDUCTORS WITH CONDUCTIVE POLYMERS AND THEIR METALLIZATION PROCESS | ATOTECH DEUTSCHLAND GMBH (DE) | 1997-10-08 | — | — | EP | disclosed |
| EP-0656025-A1 | SOLUTION FOR COATING NON CONDUCTORS WITH CONDUCTIVE POLYMERS AND THEIR METALLIZATION PROCESS. | ATOTECH DEUTSCHLAND GMBH (DE) | 1995-06-07 | — | — | EP | disclosed |
| EP-0333661-B1 | Process for the preparation of a pyrole derivative | CIBA GEIGY AG (CH) | 1994-04-27 | — | — | EP | disclosed |
| EP-0587134-A2 | Cyclic urea derivatives, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1994-03-16 | — | — | EP | disclosed |
| WO-1994004591-A1 | SOLUTION FOR COATING NON CONDUCTORS WITH CONDUCTIVE POLYMERS AND THEIR METALLIZATION PROCESS | ATOTECH DEUTSCHLAND GMBH (DE) | 1994-03-03 | — | — | WO | disclosed |
| EP-0529400-A1 | 3-(2-Chloro-3-trifluoromethyl)-4-cyanopyrrole, as insecticides | BAYER AG (DE) | 1993-03-03 | — | — | EP | disclosed |
| EP-0333661-A2 | Process for the preparation of a pyrole derivative | CIBA-GEIGY AG (CH) | 1989-09-20 | — | — | EP | disclosed |