Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.48 |
| ▸ | REN | P00797 | 19/20 | 0.46 |
| ▸ | CTSD | P07339 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7295948 | 0.99 | BACE1 (0.47) | BACE1RENCTSD | |
| SCHEMBL7294736 | 0.96 | BACE1 (0.48) | BACE1RENCTSD | |
| Hydrochloric Acid SCHEMBL7287504 | 0.95 | BACE1 (0.48) | BACE1RENCTSD | |
| SCHEMBL7292837 | 0.92 | BACE1 (0.49) | BACE1REN | |
| SCHEMBL7428760 | 0.92 | BACE1 (0.47) | BACE1REN | |
| Hydrochloric Acid SCHEMBL7286804 | 0.92 | BACE1 (0.48) | BACE1REN | |
| Hydrochloric Acid SCHEMBL7431404 | 0.91 | BACE1 (0.46) | BACE1REN | |
| SCHEMBL7287684 | 0.88 | BACE1 (0.47) | BACE1REN | |
| SCHEMBL7434424 | 0.83 | BACE1 (0.46) | BACE1RENCTSD | |
| SCHEMBL7428494 | 0.81 | BACE1 (0.45) | BACE1RENCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0264106-B1 | 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use | BANYU PHARMA CO LTD (JP) | 1994-03-16 | — | — | EP | claimed |
| US-4851387-A | RENIN INHIBITORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-07-25 | — | — | US | claimed |