Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9012956 | 0.83 | PARP1 (0.34) | — | |
| SCHEMBL7392446 | 0.81 | HTR2C (0.36) | — | |
| SCHEMBL8543289 | 0.76 | NPC1 (0.45) | NPC1MAPTRAB9A | |
| SCHEMBL8548519 | 0.76 | MAPT (0.47) | NPC1MAPTRAB9AMCL1 | |
| SCHEMBL2962557 | 0.75 | HTR2C (0.44) | NPC1MAPTRAB9A | |
| SCHEMBL7391668 | 0.75 | TSHR (0.37) | MAPT | |
| SCHEMBL8543387 | 0.75 | HRH1 (0.45) | NPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL8550810 | 0.75 | MAPT (0.46) | NPC1MAPTRAB9AMCL1 | |
| Hydrochloric Acid SCHEMBL8544100 | 0.74 | CDK8 (0.45) | NPC1MAPTRAB9A | |
| SCHEMBL8548303 | 0.74 | RAB9A (0.45) | NPC1MAPTRAB9AMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7179466-A | — | — | None | — | — | JP | disclosed |
| US-5589476-A | TREATMENT OF NAUSEA, VOMITING AND GASTROINTESTINAL DISORDERS | SYNTHELABO (FR) | 1996-12-31 | — | — | US | disclosed |
| JP-H07179466-A | IMIDAZOL-4-YLPIPERIDINE DERIVATIVE, ITS PREPARATION, AND APPLICATION THEREOF IN MEDICINE | SYNTHELABO SA | 1995-07-18 | — | — | JP | disclosed |
| EP-0646583-A1 | Derivatives of Imidezol-4-yl piperidine, their preparation and use in therapy | SYNTHELABO (FR) | 1995-04-05 | — | — | EP | disclosed |