Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 18/20 | 0.65 |
| ▸ | ITGB1 | P05556 | 12/20 | 0.65 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.55 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429058 | 0.92 | ITGA4 (0.56) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7428465 | 0.90 | ITGB1 (0.58) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7428679 | 0.85 | ITGA4 (0.51) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7431629 | 0.85 | ITGB1 (0.61) | ITGA4ITGB1ITGB7 | |
| SCHEMBL7422799 | 0.82 | ITGB1 (0.48) | ITGA4ITGB1ITGB7 | |
| SCHEMBL6742267 | 0.81 | ITGA4 (0.54) | ITGA4ITGB1ITGB7 | |
| SCHEMBL6739477 | 0.81 | ITGA4 (0.54) | ITGA4ITGB1ITGB7 | |
| SCHEMBL6739480 | 0.81 | ITGA4 (0.54) | ITGA4ITGB1ITGB7 | |
| SCHEMBL6739164 | 0.81 | ITGA4 (0.53) | ITGA4ITGB1ITGB7 | |
| SCHEMBL6745542 | 0.80 | ITGA4 (0.57) | ITGA4ITGB1ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089989-A1 | INHIBITORS OF ALPHA4BETA1 MEDIATED CELL ADHESION | PHARMACIA & UPJOHN COMPANY (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067230-A1 | INHIBITORS OF α4β1 MEDIATED CELL ADHESION | PHARMACIA & UPJOHN COMPANY (US) | 1999-12-29 | — | — | WO | disclosed |