SCHEMBL7426232

SCHEMBL7426232

CCc1nc(C(C)(C)O)c(OC(=O)O)n1Cc1ccc(-c2ccccc2C(=O)O)cc1

nearest known ligand 0.75

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7431328 0.93 PPARG (0.61) PPARG
SCHEMBL7429975 0.91 AGTR1 (0.62)
SCHEMBL683721 0.86 AGTR1 (0.61)
SCHEMBL7431029 0.83 AGTR1 (0.53)
SCHEMBL683418 0.79 AGTR1 (0.50)
Hydrochloric Acid SCHEMBL27476648 0.79 AGTR1 (0.48)
SCHEMBL7312358 0.79 AGTR1 (0.56)
SCHEMBL7886323 0.79 AGTR1 (0.57)
SCHEMBL684085 0.78 AGTR1 (0.71) PPARG
SCHEMBL7878738 0.78 AGTR1 (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0503785-B1 1-Biphenylimidazole derivatives, their preparation and their therapeutic use SANKYO CO (JP) 2001-04-25 EP claimed