Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.51 |
| ▸ | ERAP2 | Q6P179 | 6/20 | 0.51 |
| ▸ | IL1RN | P18510 | 5/20 | 0.51 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443588 | 0.89 | ERAP2 (0.51) | ERAP2IL1RNERAP1MMELTA4H | |
| SCHEMBL7443405 | 0.86 | MME (0.52) | ANPEPERAP2IL1RNERAP1MME | |
| SCHEMBL7434815 | 0.85 | ERAP2 (0.53) | ERAP2IL1RNERAP1MMELTA4H | |
| SCHEMBL7438775 | 0.83 | ERAP2 (0.54) | ANPEPERAP2IL1RNERAP1MME | |
| Ubenimex SCHEMBL16782425 | 0.82 | MME (0.66) | ANPEPMMELTA4H | |
| Ubenimex SCHEMBL7943 | 0.82 | MME (0.66) | ANPEPMMELTA4H | |
| Ubenimex SCHEMBL8191715 | 0.82 | MME (0.66) | ANPEPMMELTA4H | |
| Ubenimex SCHEMBL22632072 | 0.82 | MME (0.66) | ANPEPMMELTA4H | |
| Ubenimex SCHEMBL5807154 | 0.82 | MME (0.66) | ANPEPMMELTA4H | |
| Ubenimex SCHEMBL5812930 | 0.82 | MME (0.66) | ANPEPMMELTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4453003-A | ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS | UMEZAWA HAMAO (JP) | 1984-06-05 | — | — | US | disclosed |
| US-4391986-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediates therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-07-05 | — | — | US | disclosed |
| US-4281180-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-07-28 | — | — | US | disclosed |