Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.66 |
| ▸ | LTA4H | P09960 | 1/20 | 0.63 |
| ▸ | LAP3 | P28838 | 2/20 | 0.61 |
| ▸ | ANPEP | P15144 | 1/20 | 0.61 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.61 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ubenimex SCHEMBL7944 | 1.00 | MME (0.66) | MMELTA4HLAP3ANPEPRNPEP | |
| Ubenimex SCHEMBL8191715 | 1.00 | MME (0.66) | MMELTA4HLAP3ANPEPRNPEP | |
| Ubenimex SCHEMBL5057802 | 1.00 | MME (0.66) | MMELTA4HLAP3ANPEPRNPEP | |
| Ubenimex SCHEMBL5819609 | 1.00 | MME (0.66) | MMELTA4HLAP3ANPEPRNPEP | |
| Ubenimex SCHEMBL5812930 | 1.00 | MME (0.66) | MMELTA4HLAP3ANPEPRNPEP | |
| Ubenimex SCHEMBL9247599 | 1.00 | MME (0.66) | MMELTA4HLAP3ANPEPRNPEP | |
| Ubenimex SCHEMBL5807154 | 1.00 | MME (0.66) | MMELTA4HLAP3ANPEPRNPEP | |
| Ubenimex SCHEMBL16782424 | 1.00 | MME (0.66) | MMELTA4HLAP3ANPEPRNPEP | |
| Ubenimex SCHEMBL22632072 | 1.00 | MME (0.66) | MMELTA4HLAP3ANPEPRNPEP | |
| Ubenimex SCHEMBL7943 | 1.00 | MME (0.66) | MMELTA4HLAP3ANPEPRNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9889102-B2 | Sigma receptor ligands and methods of modulating cellular protein homeostasis using same | DREXEL UNIVERSITY (US) | 2018-02-13 | — | — | US | claimed |
| US-12398108-B2 | Compounds, compositions, and methods for treating diseases | DREXEL UNIVERSITY (US) | 2025-08-26 | — | — | US | disclosed |
| US-20210403436-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATING DISEASES | UNIV DREXEL (US) | 2021-12-30 | — | — | US | disclosed |
| US-10314795-B2 | Sigma receptor ligands and methods of modulating cellular protein homeostasis using same | DREXEL UNIVERSITY (US) | 2019-06-11 | — | — | US | disclosed |
| US-9889102-B2 | Sigma receptor ligands and methods of modulating cellular protein homeostasis using same | DREXEL UNIVERSITY (US) | 2018-02-13 | — | — | US | disclosed |
| WO-2017106312-A1 | METHODS OF MODULATING LEVELS OF IL-6 AND PD-L1 | DREXEL UNIVERSITY (US) | 2017-06-22 | — | — | WO | disclosed |
| US-9388126-B2 | Sigma receptor ligands and methods of modulating cellular protein homeostasis using same | DREXEL UNIVERSITY (US) | 2016-07-12 | — | — | US | disclosed |
| US-20150166472-A1 | NOVEL SIGMA RECEPTOR LIGANDS AND METHODS OF MODULATING CELLULAR PROTEIN HOMEOSTASIS USING SAME | DREXEL UNIVERSITY | 2015-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166472-A1 | NOVEL SIGMA RECEPTOR LIGANDS AND METHODS OF MODULATING CELLULAR PROTEIN HOMEOSTASIS USING SAME | TMEM97, SIGMAR1, ADRM1 | MME 1705/4885LTA4H 2142/4885LAP3 2746/4885 |
| US-12398108-B2 | Compounds, compositions, and methods for treating diseases | SIGMAR1, OPRK1, OPRM1 | MME 997/4885LTA4H 485/4885LAP3 2940/4885 |
| US-10314795-B2 | Sigma receptor ligands and methods of modulating cellular protein homeostasis using same | SIGMAR1, TMEM97, ADRM1 | MME 1650/4885LTA4H 2187/4885LAP3 2799/4885 |
| US-20210403436-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATING DISEASES | SIGMAR1, OPRL1, NR1H3 | MME 506/4885LTA4H 588/4885LAP3 2755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.