Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 3/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 11/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7427361 | 0.80 | PDE4D (0.39) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL7421490 | 0.79 | NFE2L2 (0.39) | PDE4APDE4DPDE4BPDE4CMAPT | |
| SCHEMBL7420906 | 0.78 | PDE4A (0.47) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL7427963 | 0.77 | PDE4A (0.39) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL7426462 | 0.74 | MEN1 (0.47) | PDE4APDE4DPDE4BPDE4CMEN1 | |
| SCHEMBL7426452 | 0.69 | PDE4D (0.46) | PDE4APDE4DPDE4BPDE4CMEN1 | |
| SCHEMBL8688573 | 0.67 | PDE4A (0.50) | ABCB1ABCG2PDE4APDE4DPDE4B | |
| SCHEMBL6886859 | 0.66 | PDE4A (0.59) | PDE4APDE4DPDE4BPDE4CMEN1 | |
| SCHEMBL27657387 | 0.66 | PDE4A (0.56) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL6882017 | 0.66 | PDE4A (0.56) | PDE4APDE4DPDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780478-A | Tetra-substituted phenyl derivatives | CELLTECH THERAPEUTICS, LIMITED (GB) | 1998-07-14 | — | — | US | claimed |