Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ME2 | P23368 | 1/20 | 0.58 |
| ▸ | ME1 | P48163 | 1/20 | 0.58 |
| ▸ | ME3 | Q16798 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7437444 | 0.88 | KMT2A (0.64) | ALDH1A1KDM4ETHRBMEN1KMT2A | |
| SCHEMBL7434820 | 0.86 | ALDH1A1 (0.68) | ME2ME1ME3ALDH1A1KDM4E | |
| SCHEMBL10917054 | 0.85 | KDM4E (0.73) | ME2ME1ME3GAAALDH1A1 | |
| SCHEMBL7441384 | 0.82 | CA1 (0.58) | ALDH1A1KDM4ETHRBMEN1KMT2A | |
| SCHEMBL7439654 | 0.82 | ALDH1A1 (0.71) | GAAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7431609 | 0.82 | NPC1 (0.51) | ALDH1A1KDM4ETHRBMEN1KMT2A | |
| SCHEMBL7434260 | 0.81 | USP2 (0.56) | ALDH1A1KDM4EMEN1KMT2AHTT | |
| SCHEMBL7435084 | 0.81 | USP2 (0.76) | ALDH1A1KMT2AHTTLMNASMN1; SMN2 | |
| SCHEMBL31559145 | 0.81 | GAA (0.67) | ME2ME1ME3GAAALDH1A1 | |
| SCHEMBL31559143 | 0.81 | GAA (0.67) | ME2ME1ME3GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |