Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL448820 | 0.80 | MAPT (0.38) | MAPTALDH1A1MEN1MITFGAA | |
| SCHEMBL449911 | 0.72 | NOTUM (0.40) | MAPTALDH1A1MEN1MITFGAA | |
| SCHEMBL5118907 | 0.69 | NR3C2 (0.37) | MAPTALDH1A1MEN1MITFGAA | |
| SCHEMBL20987885 | 0.69 | MAPT (0.30) | MAPTALDH1A1MEN1MITFGAA | |
| SCHEMBL16101587 | 0.69 | FGFR4 (0.47) | MAPTCTSDBACE1 | |
| SCHEMBL655542 | 0.69 | MEN1 (0.40) | ALDH1A1MEN1KMT2ACTSDBACE1 | |
| SCHEMBL655380 | 0.68 | CTSD (0.30) | CTSDBACE1 | |
| SCHEMBL691049 | 0.67 | NR1H2 (0.42) | — | |
| SCHEMBL4559386 | 0.66 | NR3C2 (0.43) | MEN1GAAKMT2ASMN1; SMN2NR3C2 | |
| SCHEMBL445072 | 0.66 | HTR1D (0.36) | MAPTALDH1A1GAAMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000012492-A1 | BENZOXAZINE DERIVATIVES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2000-03-09 | — | — | WO | disclosed |