Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.45 |
| ▸ | CTSK | P43235 | 4/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6786029 | 0.96 | CTSS (0.45) | CTSSCTSKSCN9AUSP2PABPC1 | |
| SCHEMBL8893975 | 0.94 | CTSS (0.41) | CTSSCTSKSCN9AUSP2MEN1 | |
| SCHEMBL8893594 | 0.94 | CTSS (0.41) | CTSSCTSKSCN9AUSP2MEN1 | |
| SCHEMBL7426423 | 0.94 | CTSS (0.41) | CTSSCTSKSCN9AUSP2MEN1 | |
| SCHEMBL8892992 | 0.90 | PPARG (0.41) | CTSSCTSKSCN9AATM | |
| SCHEMBL8892378 | 0.90 | PPARG (0.41) | CTSSCTSKSCN9AATM | |
| SCHEMBL9005035 | 0.90 | ATM (0.46) | CTSSCTSKSCN9AMEN1LMNA | |
| SCHEMBL7443701 | 0.90 | ATM (0.46) | CTSSCTSKSCN9AMEN1LMNA | |
| SCHEMBL7432732 | 0.90 | ATM (0.46) | CTSSCTSKSCN9AMEN1LMNA | |
| SCHEMBL6312228 | 0.90 | ATM (0.46) | CTSSCTSKSCN9AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| WO-1996016980-A1 | MORPHOLINOETHYLAMIDE DERIVATIVES | NOVARTIS AG (CH) | 1996-06-06 | — | — | WO | disclosed |
| EP-0532466-A2 | Derivatives of 5-amino-4-hydroxy-hexanoic acid and their therapeutical use | CIBA-GEIGY AG (CH) | 1993-03-17 | — | — | EP | disclosed |