Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.32 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8124689 | 0.96 | MEN1 (0.43) | MEN1KMT2ASLC6A3KDM4CKCNA5 | |
| SCHEMBL7768729 | 0.94 | MEN1 (0.40) | MEN1KMT2ASLC6A3KDM4CKCNA5 | |
| SCHEMBL7765828 | 0.93 | MEN1 (0.41) | MEN1KMT2ASLC6A3KDM4CKCNA5 | |
| SCHEMBL7958095 | 0.92 | MEN1 (0.44) | MEN1KMT2ASLC6A3KDM4CKCNA5 | |
| SCHEMBL8484373 | 0.89 | MEN1 (0.38) | MEN1KMT2ASLC6A3KDM4CEPHA2 | |
| SCHEMBL8207606 | 0.89 | MEN1 (0.39) | MEN1KMT2ASLC6A3KDM4CKCNA5 | |
| SCHEMBL7751872 | 0.88 | MEN1 (0.40) | MEN1KMT2ASLC6A3KDM4CKCNA5 | |
| SCHEMBL6543753 | 0.87 | MEN1 (0.38) | MEN1KMT2ASLC6A3EPHA2 | |
| SCHEMBL7765726 | 0.86 | MEN1 (0.41) | MEN1KMT2ASLC6A3KDM4CKCNA5 | |
| SCHEMBL4678659 | 0.85 | MEN1 (0.40) | MEN1KMT2ASLC6A3KDM4CSSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1101757-A1 | Heterocyclic compounds as tachykinin receptor antagonists | SANOFI-SYNTHELABO (FR) | 2001-05-23 | — | — | EP | disclosed |
| EP-0915849-A2 | PROCESS FOR THE PREPARATION OF 3,3-DISUBSTITUTED PIPERIDINES | Smithkline Beecham S.p.A. (IT) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998005640-A2 | PROCESS FOR THE PREPARATION OF 3,3-DISUBSTITUTED PIPERIDINES | SMITHKLINE BEECHAM S.P.A. (IT) | 1998-02-12 | — | — | WO | disclosed |
| EP-0723959-A1 | Heterocyclic compounds as tachykinin receptor antagonists, process for their preparation and pharmaceuticals containing them | SANOFI (FR) | 1996-07-31 | — | — | EP | disclosed |