Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 5/20 | 0.46 |
| ▸ | MMP9 | P14780 | 5/20 | 0.46 |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | MME | P08473 | 2/20 | 0.42 |
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5870089 | 0.90 | ANPEP (0.38) | MMP1MMP9MMP3ANPEP | |
| SCHEMBL5870321 | 0.90 | ANPEP (0.38) | MMP1MMP9MMP3ANPEP | |
| SCHEMBL5870317 | 0.90 | ANPEP (0.38) | MMP1MMP9MMP3ANPEP | |
| SCHEMBL5869290 | 0.88 | MAPK1 (0.44) | MMP1MMP9MMP3ACENTSR1 | |
| SCHEMBL5869703 | 0.88 | MMP1 (0.48) | MMP1MMP9MMP3NTSR1ANPEP | |
| SCHEMBL5870188 | 0.88 | MMP1 (0.48) | MMP1MMP9MMP3NTSR1ANPEP | |
| SCHEMBL5869287 | 0.88 | MAPK1 (0.44) | MMP1MMP9MMP3ACENTSR1 | |
| SCHEMBL5869299 | 0.88 | MAPK1 (0.44) | MMP1MMP9MMP3ACENTSR1 | |
| SCHEMBL5870191 | 0.88 | MMP1 (0.48) | MMP1MMP9MMP3NTSR1ANPEP | |
| SCHEMBL5869775 | 0.88 | ACE (0.47) | MMP1MMP9MMP3MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | claimed |