Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.82 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7640311 | 0.90 | TDP1 (0.80) | TDP1L3MBTL1MAPK1PTGESALOX5 | |
| SCHEMBL7434380 | 0.84 | TDP1 (0.83) | TDP1L3MBTL1MAPK1ALOX5PPARG | |
| SCHEMBL7429680 | 0.83 | TDP1 (0.81) | TDP1L3MBTL1MAPK1ALOX5PPARG | |
| SCHEMBL7635821 | 0.81 | TDP1 (0.61) | TDP1L3MBTL1MAPK1PTGESALOX5 | |
| SCHEMBL7430736 | 0.80 | TDP1 (0.91) | TDP1L3MBTL1MAPK1ALOX5PPARG | |
| SCHEMBL7429207 | 0.80 | TDP1 (0.91) | TDP1L3MBTL1MAPK1PTPN1ALDH1A1 | |
| SCHEMBL7635568 | 0.80 | TDP1 (0.63) | TDP1L3MBTL1PPARGALDH1A1KDM4E | |
| SCHEMBL8080157 | 0.78 | TDP1 (0.88) | TDP1L3MBTL1MAPK1ALDH1A1MEN1 | |
| SCHEMBL7571535 | 0.78 | TDP1 (0.88) | TDP1L3MBTL1MAPK1ALDH1A1MEN1 | |
| SCHEMBL11022539 | 0.78 | TDP1 (0.88) | TDP1L3MBTL1MAPK1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046590-A2 | Phen(alk)oxy-substituted oxirane-carboxylic acids, process for their preparation, their use and drugs containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1982-03-03 | — | — | EP | disclosed |