Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.73 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.73 |
| ▸ | TMPRSS2 | O15393 | 6/20 | 0.53 |
| ▸ | PLAU | P00749 | 2/20 | 0.52 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435004 | 0.96 | ITGB3 (0.67) | ITGB3ITGA2BTMPRSS2PLAUNOD1 | |
| SCHEMBL7432874 | 0.94 | ITGB3 (0.64) | ITGB3ITGA2BTMPRSS2PLAUNOD1 | |
| SCHEMBL7396048 | 0.91 | ITGB3 (0.74) | ITGB3ITGA2BTMPRSS2PLAUNOD1 | |
| SCHEMBL7432427 | 0.90 | ITGB3 (0.59) | ITGB3ITGA2BTMPRSS2PLAUNOD1 | |
| SCHEMBL7393893 | 0.89 | ITGB3 (0.72) | ITGB3ITGA2BTMPRSS2PLAUNOD1 | |
| SCHEMBL7394224 | 0.89 | ITGB3 (0.72) | ITGB3ITGA2BTMPRSS2PLAUNOD1 | |
| SCHEMBL7397281 | 0.87 | ITGB3 (0.68) | ITGB3ITGA2BTMPRSS2PLAUNOD1 | |
| SCHEMBL7396832 | 0.85 | ITGB3 (0.66) | ITGB3ITGA2BTMPRSS2PLAUNOD1 | |
| SCHEMBL7392173 | 0.85 | ITGB3 (0.66) | ITGB3ITGA2BTMPRSS2PLAUNOD1 | |
| SCHEMBL7399976 | 0.85 | ITGB3 (0.66) | ITGB3ITGA2BTMPRSS2PLAUNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760364-B1 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI CHEMICALS INC (JP) | 2000-07-19 | — | — | EP | disclosed |
| EP-0760364-A2 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1997-03-05 | — | — | EP | disclosed |