Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 13/20 | 0.46 |
| ▸ | PDE4A | P27815 | 9/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7427349 | 0.87 | PDE4D (0.46) | PDE4DPDE4APDE4BPDE4CPDE5A | |
| SCHEMBL7427953 | 0.86 | PDE4D (0.44) | PDE4DPDE4APDE4BPDE4CPDE5A | |
| SCHEMBL7420904 | 0.82 | PDE4A (0.53) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7426462 | 0.81 | MEN1 (0.47) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7421486 | 0.79 | PDE4D (0.44) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7427361 | 0.78 | PDE4D (0.39) | PDE4DPDE4APDE4BPDE4CPDE5A | |
| SCHEMBL7390362 | 0.78 | MEN1 (0.44) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL6887936 | 0.77 | PDE4A (0.49) | PDE4DPDE4APDE4BPDE4C | |
| Ammonia Solution, Strong SCHEMBL27921141 | 0.76 | HTR2C (0.45) | — | |
| SCHEMBL8209553 | 0.73 | PDE4A (0.56) | PDE4DPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780478-A | Tetra-substituted phenyl derivatives | CELLTECH THERAPEUTICS, LIMITED (GB) | 1998-07-14 | — | — | US | claimed |