Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | IL6 | P05231 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7486455 | 0.93 | HDAC6 (0.42) | P2RY14MEN1KMT2AUSP2HDAC6 | |
| SCHEMBL7534769 | 0.85 | HDAC6 (0.41) | P2RY14MEN1KMT2AUSP2HDAC6 | |
| SCHEMBL6595168 | 0.83 | P2RY14 (0.49) | P2RY14MEN1KMT2AUSP2HDAC6 | |
| SCHEMBL7425793 | 0.79 | P2RY14 (0.38) | P2RY14MEN1KMT2AUSP2HDAC6 | |
| SCHEMBL6598330 | 0.79 | P2RY14 (0.49) | P2RY14MEN1KMT2AUSP2HDAC6 | |
| SCHEMBL6595767 | 0.78 | KDR (0.49) | P2RY14MEN1KMT2AUSP2MAPT | |
| SCHEMBL6594949 | 0.77 | HDAC6 (0.50) | P2RY14MEN1KMT2AUSP2HDAC6 | |
| SCHEMBL2438782 | 0.76 | NPC1 (0.51) | MEN1KMT2AUSP2HDAC6MAPT | |
| SCHEMBL6597550 | 0.74 | KDR (0.49) | P2RY14MEN1KMT2AUSP2MAPT | |
| SCHEMBL6162294 | 0.73 | KMT2A (0.45) | P2RY14MEN1KMT2AUSP2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133484-A2 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS INTEGRIN INHIBITORS | AstraZeneca AB (SE) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000005223-A2 | HETEROCYCLIC DERIVATIVES AND THEIR USE AS INTEGRIN INHIBITORS | ASTRAZENECA AB (SE) | 2000-02-03 | — | — | WO | disclosed |