Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 18/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7447398 | 0.92 | CASP1 (0.53) | CASP1 | |
| SCHEMBL7427155 | 0.92 | CASP1 (0.54) | CASP1 | |
| SCHEMBL7431145 | 0.90 | MAPT (0.41) | CASP1ALDH1A1CYP3A4ATM | |
| SCHEMBL7686501 | 0.87 | CASP1 (0.51) | CASP1 | |
| Hydrochloric Acid SCHEMBL7693824 | 0.86 | CASP1 (0.50) | CASP1 | |
| SCHEMBL7444248 | 0.86 | CASP1 (0.47) | CASP1 | |
| SCHEMBL7438326 | 0.85 | CASP1 (0.50) | CASP1 | |
| SCHEMBL7434554 | 0.85 | CASP1 (0.52) | CASP1 | |
| SCHEMBL7439324 | 0.84 | CYP1A2 (0.54) | CASP1ALDH1A1 | |
| SCHEMBL8176680 | 0.83 | CASP1 (0.48) | CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710153-A | INTERLEUKIN CONVERTING ENZYME INHIBITORS | ONO PHRAMACEUTICAL CO., LTD. (JP) | 1998-01-20 | — | — | US | claimed |
| EP-0761680-A2 | Tetrazole compounds having Interleukin-1beta converting enzyme inhibitory activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-03-12 | — | — | EP | claimed |
| US-5710153-A | INTERLEUKIN CONVERTING ENZYME INHIBITORS | ONO PHRAMACEUTICAL CO., LTD. (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0761680-A2 | Tetrazole compounds having Interleukin-1beta converting enzyme inhibitory activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-03-12 | — | — | EP | disclosed |