Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL135213 | 0.90 | MAPT (0.60) | MAPTHSD17B10HTTGFERGPR55 | |
| Ethane SCHEMBL3904717 | 0.87 | MAPT (0.57) | MAPTHSD17B10HTTGFERGPR55 | |
| Hydrogen Peroxide SCHEMBL11347551 | 0.87 | MAPT (0.57) | MAPTHSD17B10HTTGFERGPR55 | |
| Methane SCHEMBL10894585 | 0.87 | MAPT (0.57) | MAPTHSD17B10HTTGFERGPR55 | |
| SCHEMBL28211191 | 0.87 | MAPT (0.57) | MAPTHSD17B10HTTGFERGPR55 | |
| SCHEMBL31482520 | 0.87 | MAPT (0.57) | MAPTHSD17B10HTTGFERGPR55 | |
| SCHEMBL9514759 | 0.83 | HSD17B1 (0.60) | MAPTHSD17B10HTTGFERGPR55 | |
| Acetone SCHEMBL10937938 | 0.83 | HSD17B1 (0.54) | MAPTHSD17B10HTTGFERGPR55 | |
| Phenol SCHEMBL10398916 | 0.81 | ESR1 (0.54) | MAPTHSD17B10HTTGFERGPR55 | |
| Acetic Acid SCHEMBL11224636 | 0.81 | CA1 (0.54) | MAPTHSD17B10HTTGFERGPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385237-A2 | 2-(1-piperazinyl)-4-phenylcycloalkanopyridine derivatives, processes for the production thereof, and pharmaceutical composition containing the same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1990-09-05 | — | — | EP | disclosed |