Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4022897 | 0.83 | CYP2C19 (0.67) | CYP2C19GAAPTGS1LMNATSHR | |
| SCHEMBL11077670 | 0.81 | CYP2C19 (0.73) | CYP2C19CA2CAMK2AGAAPTGS1 | |
| SCHEMBL5879152 | 0.81 | CYP2C19 (0.73) | CYP2C19GAAPTGS1LMNAPTGS2 | |
| SCHEMBL1458050 | 0.80 | CYP2C19 (1.00) | CYP2C19LMNAALDH1A1L3MBTL1POLB | |
| SCHEMBL1458057 | 0.80 | CYP2C19 (1.00) | CYP2C19LMNAALDH1A1L3MBTL1POLB | |
| SCHEMBL666893 | 0.80 | CYP2C19 (1.00) | CYP2C19LMNAALDH1A1L3MBTL1POLB | |
| SCHEMBL4029220 | 0.79 | CYP2C19 (0.71) | CYP2C19LMNATSHRHSD17B10L3MBTL1 | |
| SCHEMBL4265668 | 0.79 | CYP2C19 (0.71) | CYP2C19GAAPTGS1PTGS2ALDH1A1 | |
| SCHEMBL21561158 | 0.79 | CYP2C19 (0.71) | CYP2C19LMNATSHRHSD17B10L3MBTL1 | |
| SCHEMBL19803299 | 0.79 | CYP2C19 (0.71) | CYP2C19LMNATSHRHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000061631-A1 | MODIFIED PENTAPEPTIDE ANTAGONISTS OF THE ATRIAL NATRIURETIC PEPTIDE CLEARANCE RECEPTOR | ASTRAZENECA AB (SE) | 2000-10-19 | — | — | WO | disclosed |